Though the official psychedelic “era” occurred between the mid-1960s and 70s, a new age of the psychedelic advocacy remains upon us. In recent years, psychedelics have undoubtedly become increasingly popular. Cities like Denver and Detroit decriminalized certain substances, your peers are making TikToks about their morning magic mushroom microdose, and, most importantly, new therapeutic benefits also surface every day.
Psychedelic Use Contributes to Decrease in Opioid Use
Most recently, a study found that psychedelic use has been associated with a significant decrease in illicit opioid consumption. This includes LSD, psilocybin, mescaline, and also DMT.
The Vancouver-based study that was published in the Journal of International Drug Policy states that, “recent psychedelic use was associated with 55% reduced odds of daily opioid use.”
Researchers took a look at data from nearly 4,000 individuals with substance misuse disorders. Out of the 3,813 individuals involved, 1,093 reported illicit opioid consumption. Additionally, 229 individuals reported use of psychedelics in the past six months.

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This is the First Study to Link Psychedelic Use with Lowered Opioid Use
As other recent research suggests the possible benefits of psychedelics on mental issues such as depression and PTSD, these new findings also help to validate the benefits. While cannabis previously connected to reduced opioid use, this marks “the first longitudinal study to link psychedelic use with lower daily opioid use.”
The study states:
“Over study follow-up after adjusting for a range of potential confounders, psychedelic use remained independently associated with a significantly reduced odds of subsequent daily opioid use. While confirmation in other settings is required, these findings align with growing evidence that psychedelic use may be associated with detectable reductions in subsequent substance use including illicit opioid use.”
This study found naturalistic psychedelic use was independently associated with a significantly reduced odds of subsequent daily illicit opioid use among a community-based sample of people who use drugs.

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