The growing acceptance of medical cannabis has opened the door for people to explore natural alternatives to pharmaceuticals. One area where cannabis shows real promise is mental health, especially when it comes to terpenes for anxiety.
Terpenes are the organic compounds in cannabis responsible for each strain’s aroma, flavor, and unique effects. Beyond scent and taste, terpenes play a key role in shaping how cannabis impacts the body and mind. With more than 150 terpenes identified in cannabis, each strain contains its own unique terpene profile that can influence mood, relaxation, and stress response.
For people struggling with stress or panic, certain cannabis terpenes for anxiety relief have been researched for their potential calming and anti-anxiety benefits. Terpenes such as limonene, myrcene, and caryophyllene stand out for their soothing properties, making them popular in strains recommended for relaxation and mental balance.
If you’re curious about how different anti-anxiety terpenes can support mental health, this guide will break down the top calming compounds and which strains contain them.
Cannabis Terpenes That May Help Reduce Anxiety
Limonene
Limonene has been shown to be one of the terpenes in weed that helps reduce anxiety. In 2013, a study in the Pharmacology Chemistry and Behavior publication showed findings on the anti-anxiety potential of limonene when used in aromatherapy. Additionally, a study published a year later in Rejuvenation Research explored the terpene’s ability to reduce stress.
Limonene is one of the most abundant terpenes. The terpene has a zesty, citrus-like smell. Some common strains that are dominant in limonene include OG Kush, Sour Diesel, and Jack Herer.

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Myrcene
Myrcene is equally as abundant in cannabis as limonene. In 2011, a research paper published in the British Journal of Pharmacology investigated the potential anti-anxiety benefits of a combination of myrcene, limonene, and pinene. Myrcene may be a great choice for anxiety treatment due to its therapeutic properties.
Furthermore, myrcene gives off an earthy, musky aroma that resembles the smell of cloves. Strains with myrcene tend to have indica-dominant effects, such as potentially relaxing mind and body feelings. Some popular strains that contain high levels of mycrene are Grape Ape, Granddaddy Purple, OG Kush, and Blue Dream.
Caryophyllene
Also known as b-caryophyllene, this is one of the most popular terpenes that helps treat anxiety.
Caryophyllene interacts with CB2 receptors in the brain. These receptors are responsible for the non-psychoactive benefits of THC. In 2020, a study was published in the Natural Product Communications journal exploring and supporting the anti-anxiety effects of caryophyllene.
Furthermore, caryophyllene gives off a peppery, warm aroma that smells like black pepper, cinnamon, and diesel. Some strains that contain caryophyllene include Girl Scout Cookies, Bubba Kush, Chemdawg, and also Sour Diesel.
FAQ: Terpenes for Anxiety and Stress Relief
What are terpenes in cannabis?
Terpenes are natural aromatic compounds found in cannabis and other plants. They give strains their distinct flavors and aromas, while also influencing potential effects such as relaxation, focus, or stress relief.
Which terpenes are best for anxiety?
The top cannabis terpenes for anxiety include limonene (citrusy, uplifting), myrcene (earthy, calming), and caryophyllene (peppery, grounding). Other terpenes like linalool and pinene may also support relaxation and stress reduction.
How do terpenes help with anxiety?
Terpenes interact with the endocannabinoid system and work alongside cannabinoids like THC and CBD through the entourage effect. Certain terpenes may activate receptors in the brain that influence mood, stress response, and relaxation.
Is limonene good for anxiety?
Yes. Limonene is one of the most researched terpenes for anxiety relief. Studies suggest it may reduce stress and improve mood, especially when inhaled through cannabis or aromatherapy.
What strains are high in limonene?
Popular limonene-rich strains include OG Kush, Sour Diesel, Super Lemon Haze, and Jack Herer. These strains are often associated with uplifting and mood-boosting effects.
Is myrcene a calming terpene?
Yes. Myrcene is known for its sedative and muscle-relaxing qualities, which may help reduce anxiety, stress, and insomnia.
What strains contain myrcene?
Strains rich in myrcene include Granddaddy Purple, Blue Dream, Mango, and Grape Ape. Many indica-dominant strains also feature high levels of myrcene.
Does caryophyllene help with anxiety?
Yes. Caryophyllene is unique because it interacts directly with CB2 receptors in the endocannabinoid system. Research suggests it may reduce inflammation, stress, and anxiety without producing psychoactive effects.
Which strains are high in caryophyllene?
Strains with notable caryophyllene levels include Girl Scout Cookies, Bubba Kush, Chemdawg, and Sour Diesel. These strains often feature a spicy, peppery aroma.
Are there other terpenes for anxiety?
Yes. In addition to limonene, myrcene, and caryophyllene, terpenes like linalool (lavender aroma, calming) and pinene (pine aroma, focus-enhancing) may also support relaxation and stress management.
Can terpenes replace anxiety medication?
Terpenes may complement natural wellness practices but should not be considered a replacement for prescribed medication. Always consult with a medical professional before making changes to your treatment plan.
What are calming terpenes besides those for anxiety?
Calming terpenes include linalool (floral and relaxing), humulene (earthy and grounding), and terpinolene (herbal and sedative). Each may help ease stress and promote tranquility.
Are terpenes safe to use?
Yes. Terpenes are generally safe and occur naturally in cannabis, fruits, and herbs. However, sensitivity can vary, and effects may differ depending on dosage and individual body chemistry.
What is the entourage effect with terpenes?
The entourage effect refers to the way terpenes and cannabinoids work together to enhance cannabis’s overall effects. For example, a strain high in CBD and calming terpenes like myrcene may provide stronger anti-anxiety benefits than CBD alone.
Do terpenes work without THC or CBD?
Yes, terpenes have standalone properties. For example, limonene and linalool are widely used in aromatherapy. However, their effects may be amplified when combined with cannabinoids.
What terpenes are good for sleep and anxiety?
Myrcene, linalool, and terpinolene are common sleep-supporting terpenes that also help with anxiety and relaxation.
Can terpenes in weed make anxiety worse?
Yes, in some cases. Terpenes like terpinolene or high-THC strains with stimulating terpene profiles can feel too racy or intense for people prone to anxiety. Choosing balanced strains is key.
What foods contain terpenes for anxiety relief?
Many terpenes in cannabis are also found in everyday foods:
- Limonene in lemons and citrus fruits
- Myrcene in mangoes and basil
- Caryophyllene in black pepper and cloves
- Linalool in lavender
These foods may offer subtle calming benefits outside of cannabis.
How do I find strains with the right terpenes for anxiety?
Check dispensary lab reports or product menus, which often list terpene profiles. Look for strains dominant in limonene, myrcene, caryophyllene, or linalool.
Are terpenes legal?
Yes. Terpenes are legal because they are natural compounds found in plants, herbs, and fruits. Their legality is not tied to cannabis regulation.
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