Most people were introduced to Jojo Simmons on MTV’s Run’s House. The show pulled the curtain back on the Simmons family, giving the world a look at Rev Run’s household and the next generation growing up under the weight of hip-hop history. For Jojo, that early exposure came with pressure. He had to figure out who he was in front of cameras while carrying one of the most important last names in the culture.
Fast forward to today and Jojo has carved his own lane. He’s not chasing rap dreams or trying to recreate Run-DMC’s success. Instead, his work is rooted in business, advocacy, and community building.
During his recent livestream appearance and interview on the Respect My Region Podcast Network, Jojo talked about his company 3isfor, his work with the Last Prisoner Project, and how faith, family, and future shape everything he’s doing now.
Watch the full Jojo Simmons x Respect My Region interview here:
3isfor Agency: Building for the Long Term
At the center of Jojo’s career is 3isfor agency, a management and development company he co-founded. The name comes from three values he says guide his life: faith, family, and future.
That foundation makes the agency different by design. Instead of chasing short-term hype, 3isfor is about giving artists and entrepreneurs the structure and guidance to build long-term careers.
Jojo explained that too many creatives only think about their next song, video, or show. They forget about contracts, branding, and ownership.
3isfor steps in with a strategy-first approach, offering support in career development, partnerships, and mentorship.
The goal is stability and independence, not a quick moment.
This shift from artist to builder is deliberate. Jojo admitted that as a younger man he felt pressure to prove himself musically. Over time, he realized his strength wasn’t in trying to outshine his family’s legacy but in extending it—creating platforms where other artists can shine without losing control of their work.
Advocacy and the Last Prisoner Project
Beyond 3isfor, Jojo has dedicated time to advocacy, most notably through the Last Prisoner Project. The nonprofit focuses on cannabis-related criminal justice reform, fighting to free individuals serving time for non-violent cannabis offenses while the legal industry continues to boom.
Jojo was direct about the issue. The cannabis space has grown into a billion-dollar market, yet thousands of people remain incarcerated for something now celebrated and monetized. For him, that contradiction isn’t just a policy failure—it’s a moral one. Supporting the Last Prisoner Project is part of how he uses his platform to push for change and remind the culture that progress means nothing if the people most harmed are left behind.
A Different Kind of Legacy
Jojo’s work with 3isfor and LPP connects back to the Simmons family blueprint. Russell Simmons turned Def Jam into an empire by pairing artistry with business strategy. Rev Run became a cultural elder by balancing music, faith, and media. Danny Simmons made his mark in fine art. Jojo is taking those lessons and applying them to his own lane.
He’s not following the traditional path of making records and touring. Instead, he’s focusing on empowerment over entertainment and equity over exposure. His version of legacy is about building opportunities and addressing injustices that still impact the community.
During the livestream, Jojo spoke about what he’s learned along the way. Helping artists slow down, think long-term, and protect themselves from the traps that derail too many careers.
He also talked about the influence of fatherhood. Becoming a dad reshaped the way he thinks about work and responsibility.
Family isn’t just a theme in his agency’s name; it’s the lens he looks through in every decision.
Building companies and supporting reform are about more than himself—they’re about providing for his children and setting up the next generation.
Jojo Simmons has come a long way from being the teenager on reality TV. The path he’s on now blends entrepreneurship with advocacy, showing that influence is most powerful when it creates opportunities for others.
With 3isfor agency, he’s building infrastructure for artists and creatives.
With the Last Prisoner Project, he’s lending his voice to criminal justice reform.
And with his values of faith, family, and future, he’s shaping a legacy that stands on its own.